Even though researchers are aware of the analgesic results of similar compounds, it's been difficult to research conolidine given that there isn't ample of it out there from natural sources. It would make up just 0.00014% of the bark of T. divaricata The "Updated" date suggests when new information https://socialfactories.com/story5226152/the-best-side-of-what-is-conolidine