There exists a release of norepinephrine with the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors from the dorsal horn to reduce afferent soreness transmission and generate analgesia. For that reason, medication like clonidine that focus on alpha-two receptors can affect the transmission of discomfort. Applies to clonidine: oral https://alcuinn257olh6.wikidank.com/user