If a dad or mum from the proband is understood to have the pathogenic variant determined within the proband, the danger into the sibs of inheriting the pathogenic variant is 50%. Thanks to decreased penetrance, sibs who inherit the pathogenic variant may or may not establish aHUS (see Penetrance). Discrepancies https://jasperxvohy.digiblogbox.com/57272150/top-guidelines-of-ahu-s